RNASE3 antibody (AA 45-160) (Biotin)

Catalog No. ABIN1699986

Cited in 1 publication. The Biotin-conjugated Rabbit Polyclonal anti-RNASE3 antibody (ABIN1699986) specifically detects RNASE3 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for RNASE3 antibody (AA 45-160) (Biotin) (ABIN1699986)

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASE3 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RNASE3 Antibody (Biotin)

Binding Specificity: AA 45-160

Purpose: Ribonuclease 3/ECP Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ECP

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-RNASE3 antibody (Biotin) (ABIN1699986)

Fujisawa, Kashiwakura, Kita, Kikukawa, Fujitani, Sasaki-Sakamoto, Kuroda, Nunomura, Hayama, Terui, Ra, Okayama: "Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria." in: The Journal of allergy and clinical immunology, Vol. 134, Issue 3, pp. 622-633.e9, (2014) (PubMed).

Target Details for RNASE3

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Alternative Name: ECP

Background:

Synonyms: ECP, RNS3, Eosinophil cationic protein, Ribonuclease 3, RNase 3, RNASE3

Background: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

Gene ID: 6037

UniProt: P12724