KRT8 antibody (pSer74) (Biotin)

Catalog No. ABIN1700172

This anti-KRT8 antibody is a Rabbit Polyclonal antibody detecting KRT8 in WB, ELISA and IHC (fro). Suitable for Human.

Quick Overview for KRT8 antibody (pSer74) (Biotin) (ABIN1700172)

Target: KRT8 (Keratin 8 (KRT8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT8 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KRT8 Antibody (Biotin)

Binding Specificity: pSer74

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CK8 around the phosphorylation site of Ser74

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for KRT8

Target: KRT8 (Keratin 8 (KRT8))

Alternative Name: Cytokeratin 8

Background:

Synonyms: Cytokeratin 8 phospho S74, p-Cytokeratin 8 phospho S74, card2, Cardiac autoantigen 2 120kD, CK 8, CK-8, ck8, Cyk 8, cyk8, CYKER, Cytokeratin 8, Cytokeratin endo A, Cytokeratin-8, Cytokeratin8, DreK8, EndoA, k0, CYK8, k2c8, K2C8_HUMAN, k8, Keratin 8, Keratin type ii cytoskeletal 8, Keratin, type II cytoskeletal 8, Keratin-8, Keratin8, KO, Krt 2.8, Krt 8, krt8, KRT-8, MGC118110, MGC174782, MGC53564, MGC85764, sb:cb186, Type-II keratin Kb8.

Background: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

Gene ID: 3856