ARF1 antibody (AA 35-130) (Cy5)

Catalog No. ABIN1704105

This anti-ARF1 antibody is a Rabbit Polyclonal antibody detecting ARF1 in IF (cc) and IF (p). Suitable for Rat.

Quick Overview for ARF1 antibody (AA 35-130) (Cy5) (ABIN1704105)

Target: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARF1 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ARF1 Antibody (Cy5)

Binding Specificity: AA 35-130

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARF1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ARF1

Target: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Alternative Name: ARF1

Background:

Synonyms: ADP Ribosylation Factor 1, ADP-ribosylation factor 1, ARF 1, ARF1, ARF1_HUMAN, DJ133P16.1.

Background: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles.

Gene ID: 375

Pathways: Transition Metal Ion Homeostasis, Inositol Metabolic Process