Hemagglutinin antibody (AA 465-566) (Cy5.5)

Catalog No. ABIN1705284

The Cy5.5-conjugated Rabbit Polyclonal anti-Hemagglutinin antibody (ABIN1705284) specifically detects Hemagglutinin in WB, IF (p) and IF (cc). The antibody is reactive with Virus and Influenza A Virus H3N1 samples.

Quick Overview for Hemagglutinin antibody (AA 465-566) (Cy5.5) (ABIN1705284)

Target: Hemagglutinin (HA)

Reactivity: Virus, Influenza A Virus H3N1

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hemagglutinin antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-Hemagglutinin Antibody (Cy5.5)

Binding Specificity: AA 465-566

Virus Strain: A/environment/North Dakota/NWRC185233-06/2007

Cross-Reactivity: Virus

Cross-Reactivity (Details): Influenza A virus H3N1

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from hemagglutinin [Influenza A virus A/environment/North Dakota/NWRC185233-06/2007(H3N1)]

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Hemagglutinin

Target: Hemagglutinin (HA)

Alternative Name: Hemagglutinin

Target Type: Influenza Protein

Background:

Synonyms: HA, Influenza A virus H3N1, hemagglutinin, H3N1, H3N1 hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, K9URT3_9INFA.

Background: Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80 % of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.