HERC2 antibody (AA 51-200) (Cy7)

Catalog No. ABIN1707421

This Rabbit Polyclonal antibody specifically detects HERC2 in IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for HERC2 antibody (AA 51-200) (Cy7) (ABIN1707421)

Target: HERC2 (Hect Domain and RLD 2 (HERC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC2 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HERC2 Antibody (Cy7)

Binding Specificity: AA 51-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HERC2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HERC2

Target: HERC2 (Hect Domain and RLD 2 (HERC2))

Alternative Name: Herc2

Background:

Synonyms: HECT domain and RCC1 like domain containing protein 2, Hect domain and RLD 2, jdf2, p528, SHEP1, HERC2_HUMAN, E3 ubiquitin-protein ligase HERC2, HECT-type E3 ubiquitin transferase HERC2

Background: HERC2 is a belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16.

Gene ID: 8924

UniProt: O95714