CRTC3 antibody (AA 151-260) (Cy7)

Catalog No. ABIN1708242

This anti-CRTC3 antibody is a Rabbit Polyclonal antibody detecting CRTC3 in WB, IF (cc), IF (p). Suitable for Human.

Quick Overview for CRTC3 antibody (AA 151-260) (Cy7) (ABIN1708242)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC3 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CRTC3 Antibody (Cy7)

Binding Specificity: AA 151-260

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRTC3/TORC3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: CRTC3/TORC3

Background:

Synonyms: CREB regulated transcription coactivator 3, CREB-regulated transcription coactivator 3, CRTC 3, CRTC3, CRTC3_HUMAN, FLJ21868, TORC 3, TORC-3, TORC3, Transducer of CREB protein 3, Transducer of regulated cAMP response element binding protein CREB 3, Transducer of regulated cAMP response element binding protein 3, Transducer of regulated cAMP response element-binding protein 3, Transducer of regulated CREB protein 3.

Background: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.

Gene ID: 64784

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection