Stanniocalcin 2 antibody (AA 81-180) (FITC)

Catalog No. ABIN1709613

This anti-Stanniocalcin 2 antibody is a Rabbit Polyclonal antibody detecting Stanniocalcin 2 in WB, IF (cc) and IF (p). Suitable for Human.

Quick Overview for Stanniocalcin 2 antibody (AA 81-180) (FITC) (ABIN1709613)

Target: Stanniocalcin 2 (STC2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stanniocalcin 2 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Stanniocalcin 2 Antibody (FITC)

Binding Specificity: AA 81-180

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Stanniocalcin 2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Stanniocalcin 2

Target: Stanniocalcin 2 (STC2)

Alternative Name: Stanniocalcin 2

Background:

Synonyms: Stanniocalcin related protein, Stanniocalcin-2, Stanniocalcin-related protein, Stanniocalcin2, STC 2, STC related protein, STC-2, STC-related protein, STC2, STC2_HUMAN, STCRP.

Background: Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).

Gene ID: 8614

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome