FUT6 antibody (AA 101-200) (HRP)

Catalog No. ABIN1711010

The Rabbit Polyclonal anti-FUT6 antibody is suitable to detect FUT6 in samples from Human. It has been validated for IHC (p) and IHC (fro).

Quick Overview for FUT6 antibody (AA 101-200) (HRP) (ABIN1711010)

Target: FUT6 (Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) (FUT6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT6 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FUT6 Antibody (HRP)

Binding Specificity: AA 101-200

Purpose: FUT6 Polyclonal Antibody, HRP Conjugated

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FUT6/FucT-VI

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FUT6

Target: FUT6 (Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) (FUT6))

Alternative Name: FUT6

Background:

Synonyms: Alpha 1,3 fucosyltransferase, EC=2.4.1.65, FCT3A, Fuc TVI, Fucosyltransferase 6, Fucosyltransferase VI, FucT VI, Galactoside 3 L fucosyltransferase, FUT6_HUMAN.

Background: Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6).

Gene ID: 2528