MYBL2 antibody (pSer577) (HRP)

Catalog No. ABIN1711463

The Rabbit Polyclonal anti-MYBL2 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect MYBL2 in samples from Human.

Quick Overview for MYBL2 antibody (pSer577) (HRP) (ABIN1711463)

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBL2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MYBL2 Antibody (HRP)

Binding Specificity: pSer577

Predicted Reactivity: Human,Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human B MyB around the phosphorylation site of Ser577

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MYBL2

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Alternative Name: B MyB

Background:

Synonyms: B MyB phospho S577 + S581, p-B MyB phospho S577 + S581, B-Myb, BMyB, MYB L2, Myb related protein B, Myb-like protein 2, Myb-related protein B, MybB, MYBB_HUMAN, MYBL 2, Mybl2, v myb avian myeloblastosis viral oncogene homolog like 2, v myb myeloblastosis viral oncogene homolog avian like 2, v myb myeloblastosis viral oncogene homolog like 2.

Background: Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in the regulation of cell survival, proliferation, and differentiation. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes.Subunit

Gene ID: 4605

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding