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Betacellulin antibody (PE)

BTC Reactivity: Human WB Host: Rabbit Polyclonal PE
Catalog No. ABIN1712667
  • Target See all Betacellulin (BTC) Antibodies
    Betacellulin (BTC)
    Reactivity
    • 45
    • 33
    • 12
    • 2
    • 1
    Human
    Host
    • 61
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 64
    • 5
    Polyclonal
    Conjugate
    • 33
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Betacellulin antibody is conjugated to PE
    Application
    • 61
    • 20
    • 16
    • 13
    • 13
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Betacellulin
    Isotype
    IgG
    Top Product
    Discover our top product BTC Primary Antibody
  • Application Notes
    FCM(1:20-100)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Betacellulin (BTC)
    Alternative Name
    beta Cellulin (BTC Products)
    Synonyms
    BTC antibody, LOC100228121 antibody, probetacellulin antibody, Bcn antibody, betacellulin antibody, betacellulin, epidermal growth factor family member antibody, BTC antibody, LOC100228121 antibody, Btc antibody
    Background

    Synonyms: Beta cellulin, Beta cellulin precursor, BTC, BTC_HUMAN, OTTHUMP00000160600, OTTHUMP00000219057, Probetacellulin.

    Background: Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.

    Gene ID
    685
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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