Hemagglutinin antibody (AA 465-566)

Catalog No. ABIN1713350

The Rabbit Polyclonal anti-Hemagglutinin antibody is suitable to detect Hemagglutinin in samples from Influenza A Virus. It has been validated for WB, IF (p), IF (cc), IHC (p) and IHC (fro).

Quick Overview for Hemagglutinin antibody (AA 465-566) (ABIN1713350)

Target: Hemagglutinin (HA)

Reactivity: Influenza A Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hemagglutinin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Hemagglutinin Antibody

Binding Specificity: AA 465-566

Virus Strain: 2007, A, NWRC185233-06, North Dakota, environment

Purpose: H3N1 hemagglutinin Polyclonal Antibody

Cross-Reactivity: Virus

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from hemagglutinin [Influenza A virus A/environment/North Dakota/NWRC185233-06/2007(H3N1)]

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Hemagglutinin

Target: Hemagglutinin (HA)

Alternative Name: Hemagglutinin

Target Type: Influenza Protein

Background:

Synonyms: HA, Influenza A virus H3N1, hemagglutinin, H3N1, H3N1 hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, K9URT3_9INFA.

Background: Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80 % of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.