Apolipoprotein C-II antibody (AA 31-101)

Catalog No. ABIN1713367

Product Details anti-Apolipoprotein C-II Antibody

Target: Apolipoprotein C-II (APOC2)

Binding Specificity: AA 31-101

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apolipoprotein C-II antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Apolipoprotein CII/APOC2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Apolipoprotein C-II

Target: Apolipoprotein C-II (APOC2)

Alternative Name: APOC2 (APOC2 Products)

Synonyms: apoc2 antibody, apoC-II antibody, fb98g08 antibody, wu:fb52e03 antibody, wu:fb71a04 antibody, wu:fb98g08 antibody, APOC2 antibody, APO-CII antibody, APOC-II antibody, RGD1560725 antibody, APOCII antibody, Apo-CII antibody, ApoC-II antibody, apolipoprotein C-II antibody, apolipoprotein C2 antibody, apoc2 antibody, APOC2 antibody, Apoc2 antibody

Background:

Synonyms: APC 2, APC2, Apo CII, APOC 2, ApoC II, apoC-II ,APOC2, APOC2 protein, ApoCII, Apolipoprotein C II, Apolipoprotein C II precursor, ApolipoproteinCII, MGC75082,

Background: Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2). The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4). The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (57). The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8). The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10).

Gene ID: 344

Pathways: Lipid Metabolism