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HCP5 antibody (AA 1-80)

This Rabbit Polyclonal antibody specifically detects HCP5 in ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Human.
Catalog No. ABIN1713526

Quick Overview for HCP5 antibody (AA 1-80) (ABIN1713526)

Target

HCP5 (HLA Complex P5 (Non-Protein Coding) (HCP5))

Reactivity

Human

Host

  • 21
  • 3
Rabbit

Clonality

  • 23
  • 1
Polyclonal

Conjugate

  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HCP5 antibody is un-conjugated

Application

ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Binding Specificity

    • 14
    • 5
    • 3
    • 2
    AA 1-80

    Predicted Reactivity

    Human

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human HCP5

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    HCP5 (HLA Complex P5 (Non-Protein Coding) (HCP5))

    Alternative Name

    HCP5

    Background

    Synonyms: HLA class I histocompatibility antigen protein P5, HLA complex protein P5, Protein P5 1, HCP5_HUMAN.

    Background: HCP5 is a region present on chromosome 6p21.3 that is characterized by multiple duplicated gene families. HCP5 (HLA class I histocompatibility antigen protein P5), also known as P5-1, is a 132 amino acid protein that is encoded by a gene mapping to human chromosome 6p21.33. Localizing within the MHC class I region, HCP5 is not structurally related to other MHC class I genes, but does have high sequence similarity with HERV-L and HERV-16. HCP5 also has high sequence homology to retroviral Pol genes, making it a possible candidate for interaction with HIV-1 through an antisense mechanism that prevents retrovirus transcription. Single-nucleotide polymorphisms (SNPs) to the region of the HCP5 gene that corresponds with HLA-B has been linked to a lower HIV-1 viral set point. HCP5 is highly expressed in lymphoid tissues, spleen and activated lymphocytes, as well as B-cell and natural killer (NK) cell lines.

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