HERC2 antibody (AA 51-200)

Catalog No. ABIN1713530

The Rabbit Polyclonal anti-HERC2 antibody is suitable to detect HERC2 in samples from Human. It has been validated for IF (cc), IF (p), ELISA, IHC (p), IHC (fro) and ICC.

Quick Overview for HERC2 antibody (AA 51-200) (ABIN1713530)

Target: HERC2 (Hect Domain and RLD 2 (HERC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC2 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-HERC2 Antibody

Binding Specificity: AA 51-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HERC2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HERC2

Target: HERC2 (Hect Domain and RLD 2 (HERC2))

Alternative Name: HERC2

Background:

Synonyms: HECT domain and RCC1 like domain containing protein 2, Hect domain and RLD 2, jdf2, p528, SHEP1, HERC2_HUMAN, E3 ubiquitin-protein ligase HERC2, HECT-type E3 ubiquitin transferase HERC2

Background: HERC2 is a belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16.

Gene ID: 8924

UniProt: O95714