HERC4 antibody (AA 301-400)

Catalog No. ABIN1713665

The Rabbit Polyclonal anti-HERC4 antibody has been validated for ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It is suitable to detect HERC4 in samples from Human.

Quick Overview for HERC4 antibody (AA 301-400) (ABIN1713665)

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-HERC4 Antibody

Binding Specificity: AA 301-400

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HERC4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HERC4

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Alternative Name: HERC4

Background:

Synonyms: DKFZP564G092, HECT and RLD domain containing E3 ubiquitin protein ligase 4, HECT domain and RCC1 like domain containing protein 4, HECT domain and RCC1-like domain-containing protein 4, Hect domain and RLD 4, HERC 4, HERC4, HERC4_HUMAN, KIAA1593, Probable E3 ubiquitin protein ligase HERC4, Probable E3 ubiquitin-protein ligase HERC4.

Background: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).

Gene ID: 26091