FAF2 antibody (AA 81-180)

Catalog No. ABIN1713972

Product Details anti-FAF2 Antibody

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Binding Specificity: AA 81-180

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ETEA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FAF2

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Alternative Name: ETEA (FAF2 Products)

Synonyms: FAF2 antibody, UBXD8 antibody, ETEA antibody, UBXN3B antibody, 2210404D11Rik antibody, AI462440 antibody, Ubxd8 antibody, mKIAA0887 antibody, 2210404d11rik antibody, RGD1306577 antibody, UBX8 antibody, etea antibody, ubxd8 antibody, ubxn3b antibody, Fas associated factor family member 2 antibody, Fas associated factor family member 2 S homeolog antibody, FAF2 antibody, Faf2 antibody, faf2.S antibody

Background:

Synonyms: AI462440, expressed in T cells and eosinophils in atopic dermatitis, faf2, FAF2_HUMAN, Fas associated factor family member 2, FAS-associated factor 2, KIAA0887, Protein ETEA, Protein expressed in T cells and eosinophils in atopic dermatitis, Protein expressed in T-cells and eosinophils in atopic dermatitis, UBX domain containing 8, UBX domain protein 3B, UBX domain-containing protein 3B, UBX domain-containing protein 8, UBXD8, UBXN3B.

Background: ETEA is a 445-amino acid protein associated with atopic dermatitis (AD), a chronic noncontagious relapsing inflammatory skin disease characterized by eczematous skin lesions and also referred to as eczematous dermatitis. Other atopic diseases such as hay fever, asthma and conjunctivitis often occur along with AD. ETEA shows higher expression in T cells and eosinophils of patients with AD than in T cells and eosinophils of unaffected individuals. T cells are influential in the regulation of the inflammatory process of this disease. The persistence of jAD is attributed to dysregulated apoptosis in T cells, eosinophils, and keratinocytes. ETEA may be involved in the resistance to apoptosis in T cells and eosinophils of AD patients.

Gene ID: 23197