IDH3G antibody (AA 261-360)

Catalog No. ABIN1714201

This Rabbit Polyclonal antibody specifically detects IDH3G in ELISA, WB, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for IDH3G antibody (AA 261-360) (ABIN1714201)

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDH3G antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IDH3G Antibody

Binding Specificity: AA 261-360

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IDH3G

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IDH3G

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Alternative Name: IDH3G

Background:

Synonyms: H IDHG, IDH gamma, IDH3G, IDH3G_HUMAN, Isocitrate dehydrogenase [NAD] subunit gamma, Isocitrate dehydrogenase [NAD] subunit gamma,mitochondrial, Isocitrate dehydrogenase 3 NAD+ gamma, Isocitric dehydrogenase, Isocitric dehydrogenase subunit gamma, mitochondrial, NAD H specic isocitrate dehydrogenase gamma subunit, NAD+ specic ICDH, NAD+-specic ICDH subunit gamma, NAD+ specic ICDH, OTTHUMP00000025984, OTTHUMP00000025985, OTTHUMP00000025987, OTTHUMP00000025988, OTTHUMP00000214764.

Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq, Jul 2008].