IDH3G antibody (C-Term)

Catalog No. ABIN952962

The Rabbit Polyclonal anti-IDH3G antibody (ABIN952962) specifically detects IDH3G in WB, FACS and EIA. The antibody is reactive with Human samples.

Quick Overview for IDH3G antibody (C-Term) (ABIN952962)

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDH3G antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-IDH3G Antibody

Binding Specificity: AA 364-393, C-Term

Specificity: This antibody recognizes Human Isocitric dehydrogenase gamma / IDH3G (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 364~393 amino acids from the C-terminal region of human IDH3G

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IDH3G

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Alternative Name: Isocitric Dehydrogenase gamma / IDH3G

Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia.Synonyms: NAD(+)-specific ICDH gamma, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma

Molecular Weight: 42794 Da

Gene ID: 3421

NCBI Accession: NP_004126