Tyrosinase-Related Protein 1 antibody (AA 101-200)

Catalog No. ABIN1714403

The Rabbit Polyclonal anti-Tyrosinase-Related Protein 1 antibody has been validated for WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) and ICC. It is suitable to detect Tyrosinase-Related Protein 1 in samples from Human and Mouse. There are 2+ publications available.

Quick Overview for Tyrosinase-Related Protein 1 antibody (AA 101-200) (ABIN1714403)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosinase-Related Protein 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC)

Product Details anti-Tyrosinase-Related Protein 1 Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Tyrosinase-related protein 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Tyrosinase-Related Protein 1 antibody (ABIN1714403)

Cui, Song, Geng, Ding, Qin, Fan, Dong, Geng: "The expression of KRT2 and its effect on melanogenesis in alpaca skins." in: Acta histochemica, Vol. 118, Issue 5, pp. 505-12, (2016) (PubMed).

Han, Sung, Lee: "Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells." in: Journal of food science, Vol. 81, Issue 8, pp. H2085-92, (2016) (PubMed).

Target Details for Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Alternative Name: TRP1

Background:

Synonyms: TRP, CAS2, CATB, GP75, OCA3, TRP1, TYRP, b-PROTEIN, 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, Catalase B, Glycoprotein 75, Melanoma antigen gp75, Tyrosinase-related protein 1, TRP-1, TYRP1, TYRRP

Background: Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.

Gene ID: 7306

UniProt: P17643