IDO1 antibody (AA 101-200)

Catalog No. ABIN1714836

This anti-IDO1 antibody is a Rabbit Polyclonal antibody detecting IDO1 in WB, ELISA, IHC (p), FACS, ICC, IF (p), IF (cc) and IHC (fro). Suitable for Human, Mouse and Sheep. This Primary Antibody has been cited in 4+ publications.

Quick Overview for IDO1 antibody (AA 101-200) (ABIN1714836)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivity: Human, Mouse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IDO1 Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Sheep

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IDO

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IDO1 antibody (ABIN1714836)

Lam, Li, Tipoe, Youdim, Fung: "Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration." in: PLoS ONE, Vol. 12, Issue 6, pp. e0177940, (2017) (PubMed).

Jiang, Zhao, Lin, Hu, Che, Li, Wang, Xu, Zhang, Peng: "Expression of indoleamine 2,3-dioxygenase in a murine model of Aspergillus fumigatus keratitis." in: International journal of ophthalmology, Vol. 9, Issue 4, pp. 491-6, (2016) (PubMed).

Lam, Tipoe, Wong, Youdim, Fung: "M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus." in: PLoS ONE, Vol. 11, Issue 11, pp. e0166966, (2016) (PubMed).

Fu, Zhang, Song, Sheng, Li, Li, Song, Wang, Chu, Wei: "Effect of bone marrow-derived CD11b(+)F4/80 (+) immature dendritic cells on the balance between pro-inflammatory and anti-inflammatory cytokines in DBA/1 mice with collagen-induced arthritis." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 63, Issue 5, pp. 357-67, (2014) (PubMed).

Target Details for IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Alternative Name: IDO

Background:

Synonyms: IDO, INDO, IDO-1, Indoleamine 2,3-dioxygenase 1, Indoleamine-pyrrole 2,3-dioxygenase, IDO1

Background: Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.

Gene ID: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation