TBX3 antibody (AA 101-200)

Catalog No. ABIN1714884

Cited in 1 publication. The Rabbit Polyclonal anti-TBX3 antibody (ABIN1714884) specifically detects TBX3 in FACS, IHC (p), IHC (fro), IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for TBX3 antibody (AA 101-200) (ABIN1714884)

Target: TBX3 (T-Box 3 (TBX3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TBX3 Antibody

Binding Specificity: AA 101-200

Purpose: TBX3 Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBX3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TBX3 antibody (ABIN1714884)

Moreno-Marín, Barrasa, Morales-Hernández, Paniagua, Blanco-Fernández, Merino, Fernández-Salguero: "Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis." in: Scientific reports, Vol. 7, Issue 1, pp. 10420, (2019) (PubMed).

Target Details for TBX3

Target: TBX3 (T-Box 3 (TBX3))

Alternative Name: TBX3

Background:

Synonyms: T-box protein 3, T-box transcription factor TBX3, TBX3, TBX3-ISO, TBX3 ISO, UMS, XHL, Bladder cancer related protein XHL, T box 3, TBX3_HUMAN.

Background: Tbx3 gene is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. Tbx3 is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development