BRCA1 antibody (full length)

Catalog No. ABIN1721469

The Mouse Monoclonal anti-BRCA1 antibody (Clone 1D12) (ABIN1721469) specifically detects BRCA1 in WB and IP. The antibody is reactive with Human samples.

Quick Overview for BRCA1 antibody (full length) (ABIN1721469)

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BRCA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 1D12

Product Details anti-BRCA1 Antibody

Binding Specificity: AA 341-748, full length

Specificity: Reacts with human BRCA1.

Purification: Purified

Immunogen: GST fusion protein expressed in E. coli corresponding to aa 341-748 of full-length BRCA1.

Isotype: IgG1 kappa

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IP(1 - 10 μg/mL) WB(1 - 10 μg/mL)

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -80 °C

Storage Comment: Stable for at least one year at -70°C. Avoid multiple freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BRCA1

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Alternative Name: BRCA1

Background: Breast cancer type 1 susceptibility protein RING finger protein 53 Gene name: BRCA1, RNF53 BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP

Gene ID: 672

UniProt: P38398

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus