GABBR2 antibody (AA 861-912)
Quick Overview for GABBR2 antibody (AA 861-912) (ABIN1721530)
Target
See all GABBR2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 861-912
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Specificity
- Reacts with human GABA(B)R2. Cross-reacts with mouse and rat protein. Do not cross-react with GABA(B)R1.
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Purification
- Purified (protein G)
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Immunogen
- Fusion protein corresponding to aa 861-912 of rat GABA(B)R2 (accession no. NP_113990.1).
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Isotype
- IgG1
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1 -5 μg/mL) WB(1 - 2 μg/mL)
Positive control: Rat brain membranes. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, glycerol 50 % .
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Dilute in PBS or medium that is identical to that used in the assay system.
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Storage
- -20 °C
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Storage Comment
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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Expiry Date
- 12 months
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- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
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Alternative Name
- GABA(B)R2
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Background
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GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B), and GABA(C). GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 in which GABA(B)R1 binds a ligand and GABA(B)R2 is the primary G protein contact site.
Gamma-aminobutyric acid type B receptor subunit 2 GABA-B receptor 2 GABA-B-R2, GABA-BR2, GABABR2, Gb2 G-protein coupled receptor 51 HG20 Gene name : GABBR2 -
Gene ID
- 9568
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UniProt
- O75899
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Pathways
- cAMP Metabolic Process
Target
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