MSH6 antibody
(2 references)Quick Overview for MSH6 antibody (ABIN1724694)
Target
See all MSH6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- MSH6 Antibody
-
Purification
- Ascitic fluid
-
Immunogen
- Purified recombinant fragment of MSH6 expressed in E. Coli.
-
Isotype
- IgG1
-
-
anti-MutS Homolog 6 (E. Coli) (MSH6) antibody
MSH6 Reactivity: Human WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 3E1 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reactivity: Human WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 7D9H5 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 2E3A10 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 931-1030) antibodyMSH6 Reactivity: Human WB, IF, ELISA, PLA Host: Mouse Monoclonal 1F2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reactivity: Human WB, IHC, IF, ELISA Host: Mouse Monoclonal MSH6-3091 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 217-395) antibodyMSH6 Reactivity: Human, Mouse, Monkey WB, ELISA, FACS Host: Mouse Monoclonal 1D1C2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (Internal Region) antibodyMSH6 Reactivity: Human, Mouse, Rat WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1310-1360) antibodyMSH6 Reactivity: Human WB, IHC, FACS, ICC, IP Host: Rabbit Monoclonal BLR117H unconjugated Recombinant Antibody
anti-MutS Homolog 6 (E. Coli) (MSH6) (N-Term) antibodyMSH6 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1310-1360) antibodyMSH6 Reactivity: Human WB, IHC, FACS, ICC, IP Host: Rabbit Monoclonal BLR117H unconjugated Recombinant Antibody
-
-
Application Notes
- ELISA: 1/10000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Ascitic fluid containing 0.03 % sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).
: "What the physician needs to know about Lynch syndrome: an update." in: Oncology (Williston Park, N.Y.), Vol. 19, Issue 4, pp. 455-63; discussion 463-4, 466, 469, (2005) (PubMed).
-
-
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
-
Alternative Name
- MSH6
-
Background
- Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
-
Gene ID
- 2956
-
UniProt
- P52701
-
Pathways
- DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
Target
-
