MAP1LC3A antibody (AA 1-121)

Catalog No. ABIN1724767

This Mouse Monoclonal antibody specifically detects MAP1LC3A in IHC, ELISA and FACS. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for MAP1LC3A antibody (AA 1-121) (ABIN1724767)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAP1LC3A antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 5B10D8

Product Details anti-MAP1LC3A Antibody

Binding Specificity: AA 1-121

Purpose: MAP1LC3A Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAP1LC3A (AA: 1-121) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MAP1LC3A antibody (ABIN1724767)

Jiang, Shao, Wang, Yan, Liu: "Decreased expression of Beclin-1 and LC3 in human lung cancer." in: Molecular biology reports, Vol. 39, Issue 1, pp. 259-67, (2011) (PubMed).

Han, Sun, Wang, Cai, Lou, Sun, Zhao: "Overexpression of microtubule-associated protein-1 light chain 3 is associated with melanoma metastasis and vasculogenic mimicry." in: The Tohoku journal of experimental medicine, Vol. 223, Issue 4, pp. 243-51, (2011) (PubMed).

Target Details for MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Alternative Name: MAP1LC3A

Background: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Molecular Weight: 14.3 kDa

Gene ID: 84557

UniProt: Q9H492

Pathways: Autophagy