IL3RA antibody (Interleukin 3 Receptor, alpha (Low Affinity)) (AA 200-305)

Details for Product anti-IL3RA Antibody No. ABIN1724855
Antigen
Epitope
AA 200-305
15
14
11
8
8
8
7
6
6
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
193
30
7
1
Host
Mouse
111
89
4
1
Clonality (Clone)
Monoclonal ()
Conjugate
This IL3RA antibody is un-conjugated
17
16
15
13
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
115
77
59
47
26
20
13
13
8
8
6
6
5
4
4
3
2
1
1
1
1
Options
Immunogen Purified recombinant fragment of human IL3RA (AA 200-305) expressed in E. Coli.
Clone 8E11C5
Isotype IgG1
Purification Purified
Antigen
Alternative Name IL3RA (IL3RA Antibody Abstract)
Background The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. , , , ,
Molecular Weight 43.3 kDa
Gene ID 3563
HGNC 3563
Pathways JAK-STAT Signaling
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Interleukin 3 Receptor, alpha (Low Affinity) (IL3RA) (AA 200-305) antibody (ABIN1724855) Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using IL3RA ...
Image no. 2 for anti-Interleukin 3 Receptor, alpha (Low Affinity) (IL3RA) (AA 200-305) antibody (ABIN1724855) Immunohistochemical analysis of paraffin-embedded lung cancer tissues using IL3RA mou...
Product cited in: Venkataraman, Aguhar, Kreitman, Yuan, Stetler-Stevenson: "Characteristic CD103 and CD123 expression pattern defines hairy cell leukemia: usefulness of CD123 and CD103 in the diagnosis of mature B-cell lymphoproliferative disorders." in: American journal of clinical pathology, Vol. 136, Issue 4, pp. 625-30, 2011 (PubMed).

Yue, Fu, Wang, Li, Hu, Fu, Shao: "Expression of CD123 and CD114 on the bone marrow cells of patients with myelodysplastic syndrome." in: Chinese medical journal, Vol. 123, Issue 15, pp. 2034-7, 2010 (PubMed).