DNMT1 antibody (AA 1448-1594)

Catalog No. ABIN1724879

The Mouse Monoclonal anti-DNMT1 antibody has been validated for WB, IHC and ELISA. It is suitable to detect DNMT1 in samples from Human and Monkey. There is 1 publication available.

Quick Overview for DNMT1 antibody (AA 1448-1594) (ABIN1724879)

Target: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This DNMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 7C11A2

Product Details anti-DNMT1 Antibody

Binding Specificity: AA 1448-1594

Purpose: DNMT1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DNMT1 (AA: 1448-1594) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-DNMT1 antibody (ABIN1724879)

He, Wang, Yang, Guo, Wan, Ke, Xu, Hu, Xu, Shen, Wang: "Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer." in: PLoS ONE, Vol. 6, Issue 11, pp. e27684, (2011) (PubMed).

Target Details for DNMT1

Target: DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

Alternative Name: DNMT1

Background: DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 183.2 kDa

Gene ID: 1786

UniProt: P26358

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection