Keratin 5 (KRT5) (AA 316-590) antibody

Details for Product No. ABIN1724880
Antigen
Epitope
AA 316-590
20
17
15
9
6
5
4
4
4
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
248
109
66
15
14
14
5
5
4
4
4
3
3
3
3
2
2
1
1
Host
Mouse
140
116
6
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
19
9
6
6
6
6
6
6
2
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
186
123
96
56
41
40
23
15
13
9
7
3
3
2
1
1
Options
Immunogen Purified recombinant fragment of human CK5 (AA 316-590) expressed in E. Coli.
Clone 10C11E6
Isotype IgG1
Purification Purified
Antigen
Alternative Name CK5 (KRT5 Antibody Abstract)
Background The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. ,
Molecular Weight 62.3 kDa
Gene ID 3852
HGNC 3852
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724880) Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CK5 mo...
Image no. 2 for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724880) Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using CK5 ...
Product cited in: Alam, Sehgal, Kundu, Dalal, Vaidya: "Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells." in: Molecular biology of the cell, Vol. 22, Issue 21, pp. 4068-78, 2011 (PubMed).

Grin, OMalley, Mulligan: "Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy." in: The American journal of surgical pathology, Vol. 33, Issue 11, pp. 1615-23, 2009 (PubMed).