ZEB1 antibody (AA 967-1108)

Catalog No. ABIN1724885

The Mouse Monoclonal anti-ZEB1 antibody has been validated for IHC, ELISA, ICC and FACS. It is suitable to detect ZEB1 in samples from Human. There are 2+ publications available.

Quick Overview for ZEB1 antibody (AA 967-1108) (ABIN1724885)

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZEB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 2A8A6

Product Details anti-ZEB1 Antibody

Binding Specificity: AA 967-1108

Purpose: ZEB1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ZEB1 (AA: 967-1108) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ZEB1 antibody (ABIN1724885)

Liu, Yan, Liu, Zhou, Liu, Pang, Cao, Liu, Wang, Liu, Zhang: "Lentivirus-delivered ZEB-1 small interfering RNA inhibits lung adenocarcinoma cell growth in vitro and in vivo." in: Journal of cancer research and clinical oncology, Vol. 138, Issue 8, pp. 1329-38, (2012) (PubMed).

Jia, Liu, Kong, Li: "Overexpression of ZEB1 associated with metastasis and invasion in patients with gastric carcinoma." in: Molecular and cellular biochemistry, Vol. 366, Issue 1-2, pp. 223-9, (2012) (PubMed).

Target Details for ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Alternative Name: ZEB1

Background: This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 124 kDa

Gene ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation