DIS3L2 antibody (DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2) (AA 27-250)

Details for Product anti-DIS3L2 Antibody No. ABIN1724900
Antigen
Epitope
AA 27-250
4
3
2
1
1
1
1
Reactivity
Human
38
19
18
2
1
1
Host
Mouse
26
12
Clonality (Clone)
Monoclonal ()
Conjugate
This DIS3L2 antibody is un-conjugated
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
15
13
9
8
6
3
Options
Immunogen Purified recombinant fragment of human DIS3L2 (AA 27-250) expressed in E. Coli.
Clone 6C7B2
Isotype IgG1
Purification Purified
Antigen
Alternative Name DIS3L2 (DIS3L2 Antibody Abstract)
Background The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. ,
Molecular Weight 99.3 kDa
Gene ID 129563
HGNC 129563
Pathways Stem Cell Maintenance
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) (AA 27-250) antibody (ABIN1724900) Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using DI...
Image no. 2 for anti-DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) (AA 27-250) antibody (ABIN1724900) Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using DIS3L2...
Product cited in: Du Toit: "Cytoskeleton: Formins induce nuclear actin assembly." in: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, 2013 (PubMed).

Astuti, Morris, Cooper, Staals, Wake, Fews, Gill, Gentle, Shuib, Ricketts, Cole, van Essen, van Lingen, Neri, Opitz, Rump, Stolte-Dijkstra, Müller, Pruijn, Latif, Maher: "Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility." in: Nature genetics, Vol. 44, Issue 3, pp. 277-84, 2012 (PubMed).