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DIS3L2 antibody (AA 27-250)

DIS3L2 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 6C7B2 unconjugated
Catalog No. ABIN1724900
  • Target See all DIS3L2 Antibodies
    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
    Binding Specificity
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 27-250
    Reactivity
    • 36
    • 20
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 28
    • 8
    • 1
    Mouse
    Clonality
    • 30
    • 7
    Monoclonal
    Conjugate
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DIS3L2 antibody is un-conjugated
    Application
    • 25
    • 13
    • 7
    • 6
    • 4
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. coli.
    Clone
    6C7B2
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Du Toit: "Cytoskeleton: Formins induce nuclear actin assembly." in: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, (2013) (PubMed).

    Astuti, Morris, Cooper, Staals, Wake, Fews, Gill, Gentle, Shuib, Ricketts, Cole, van Essen, van Lingen, Neri, Opitz, Rump, Stolte-Dijkstra, Müller, Pruijn, Latif, Maher: "Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility." in: Nature genetics, Vol. 44, Issue 3, pp. 277-84, (2012) (PubMed).

  • Target
    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
    Alternative Name
    DIS3L2 (DIS3L2 Products)
    Synonyms
    RGD1560168 antibody, DIS3L2 antibody, DKFZp469O0522 antibody, FAM6A antibody, PRLMNS antibody, hDIS3L2 antibody, 4930429A22Rik antibody, 8030493P09Rik antibody, DIS3-like 3'-5' exoribonuclease 2 antibody, DIS3 like 3'-5' exoribonuclease 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, DIS3L2 antibody, LOC100344728 antibody
    Background

    Description: The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. ,

    Aliases: FAM6A, PRLMNS

    Molecular Weight
    99.3 kDa
    Gene ID
    129563
    HGNC
    129563
    Pathways
    Stem Cell Maintenance
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