Paraoxonase 1 (PON1) (AA 20-155) antibody

Details for Product No. ABIN1724910
Antigen
Epitope
AA 20-155
10
10
10
9
8
7
7
5
5
4
4
4
3
2
2
1
Reactivity
Human
160
63
50
4
3
3
3
3
3
1
Host
Mouse
133
46
10
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
20
10
6
4
4
4
4
4
4
4
3
3
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
148
82
70
41
29
13
8
8
7
6
5
2
2
1
1
1
Options
Immunogen Purified recombinant fragment of human PON1 (AA 20-155) expressed in E. Coli.
Clone 4G8D3
Isotype IgG1
Purification Purified
Antigen
Alternative Name PON1 (PON1 Antibody Abstract)
Background The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. ,
Molecular Weight 39.7 kDa
Gene ID 5444
HGNC 5444
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Paraoxonase 1 (PON1) (AA 20-155) antibody (ABIN1724910) Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using PON...
Image no. 2 for anti-Paraoxonase 1 (PON1) (AA 20-155) antibody (ABIN1724910) Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using PON1 mo...
Product cited in: Yesilova, Turan, Ucmak, Selek, Halil Yavuz, Tanr?kulu: "Reduced serum paraoxonase-1 levels in vitiligo: further evidence of oxidative stress." in: Redox report : communications in free radical research, Vol. 17, Issue 5, pp. 214-8, 2012 (PubMed).

Saadat: "Paraoxonase 1 genetic polymorphisms and susceptibility to breast cancer: a meta-analysis." in: Cancer epidemiology, Vol. 36, Issue 2, pp. e101-3, 2012 (PubMed).