PON1 antibody (AA 20-155)

Catalog No. ABIN1724910

Product Details anti-PON1 Antibody

Target: PON1 (Paraoxonase 1 (PON1))

Binding Specificity: AA 20-155

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human PON1 (AA: 20-155) expressed in E. coli.

Clone: 4G8D3

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-PON1 antibody (ABIN1724910)

Yesilova, Turan, Ucmak, Selek, Halil Yavuz, Tanr?kulu: "Reduced serum paraoxonase-1 levels in vitiligo: further evidence of oxidative stress." in: Redox report : communications in free radical research, Vol. 17, Issue 5, pp. 214-8, (2012) (PubMed).

Saadat: "Paraoxonase 1 genetic polymorphisms and susceptibility to breast cancer: a meta-analysis." in: Cancer epidemiology, Vol. 36, Issue 2, pp. e101-3, (2012) (PubMed).

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: PON1 (PON1 Products)

Synonyms: esa antibody, pon antibody, pon2 antibody, MGC53915 antibody, MGC89222 antibody, PON1 antibody, ESA antibody, MVCD5 antibody, PON antibody, Pon antibody, paraoxonase 2 antibody, paraoxonase 1 antibody, pon2 antibody, PON1 antibody, Pon1 antibody

Background:

Description: The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. ,

Aliases: ESA, PON, MVCD5

Molecular Weight: 39.7 kDa

Gene ID: 5444

HGNC: 5444