PON1 antibody (AA 118-145)

Catalog No. ABIN654641

There is 1 publication for this product available. The Rabbit Polyclonal anti-PON1 antibody is suitable to detect PON1 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for PON1 antibody (AA 118-145) (ABIN654641)

Target: PON1 (Paraoxonase 1 (PON1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB28448

Product Details anti-PON1 Antibody

Binding Specificity: AA 118-145

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PON1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human PON1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PON1 antibody (ABIN654641)

Guglielmetti, Mazza, Pagano, Carrella, Sciuto, Nodari, Pezzolato, Richelmi, Baioni, Caramelli, Acutis, Bozzetta: "Identification by a proteomic approach of a plasma protein as a possible biomarker of illicit dexamethasone treatment in veal calves." in: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, Vol. 31, Issue 5, pp. 833-8, (2014) (PubMed).

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: PON1

Background: The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Molecular Weight: 39731

Gene ID: 5444

NCBI Accession: NP_000437

UniProt: P27169