MLXIPL antibody (AA 18-143)

Catalog No. ABIN1724913

This anti-MLXIPL antibody is a Mouse Monoclonal antibody detecting MLXIPL in ELISA and ICC. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for MLXIPL antibody (AA 18-143) (ABIN1724913)

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLXIPL antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC)

Clone: 5D12D1

Product Details anti-MLXIPL Antibody

Binding Specificity: AA 18-143

Purpose: MLXIPL Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MLXIPL antibody (ABIN1724913)

Noordeen, Meur, Rutter, Leclerc: "Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).

Hurtado del Pozo, Vesperinas-García, Rubio, Corripio-Sánchez, Torres-García, Obregon, Calvo: "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity." in: Biochimica et biophysica acta, Vol. 1811, Issue 12, pp. 1194-200, (2011) (PubMed).

Target Details for MLXIPL

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Alternative Name: MLXIPL

Background: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

Molecular Weight: 93.1 kDa

UniProt: Q9NP71

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process