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CD14 antibody (AA 20-214)

This anti-CD14 antibody is a Mouse Monoclonal antibody detecting CD14 in IHC, ELISA and ICC. Suitable for Human. This Primary Antibody has been cited in 2+ publications.
Catalog No. ABIN1724922

Quick Overview for CD14 antibody (AA 20-214) (ABIN1724922)

Target

See all CD14 Antibodies
CD14

Reactivity

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Human

Host

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  • 79
  • 16
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  • 1
  • 1
  • 1
Mouse

Clonality

  • 296
  • 76
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Monoclonal

Conjugate

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This CD14 antibody is un-conjugated

Application

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Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone

1H5D8
  • Binding Specificity

    • 59
    • 12
    • 8
    • 5
    • 5
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    • 4
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    • 2
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    AA 20-214

    Purpose

    CD14 Antibody

    Purification

    Purified antibody

    Immunogen

    Purified recombinant fragment of human CD14 (AA: 20-214) expressed in E. Coli.

    Isotype

    IgG2a
  • Application Notes

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Matthews, Chung, Klasse, Moore, Sanders: "Potent induction of antibody-secreting B cells by human dermal-derived CD14+ dendritic cells triggered by dual TLR ligation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 12, pp. 5729-44, (2012) (PubMed).

    Haghparast, Heidari Kharaji, Malvandi: "Down-regulation of CD14 transcripts in human glioblastoma cell line U87 MG." in: Iranian journal of immunology : IJI, Vol. 8, Issue 2, pp. 111-9, (2011) (PubMed).

  • Target

    CD14

    Alternative Name

    CD14

    Background

    The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein.



    Molecular Weight

    40 kDa

    Gene ID

    929

    UniProt

    P08571

    Pathways

    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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