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ADRA1B antibody (1st Cytoplasmic Domain)

The Rabbit Polyclonal anti-ADRA1B antibody is suitable to detect ADRA1B in samples from Human. It has been validated for IHC (p).
Catalog No. ABIN1731572
$870.72
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 12 to 16 Business Days

Quick Overview for ADRA1B antibody (1st Cytoplasmic Domain) (ABIN1731572)

Target

See all ADRA1B Antibodies
ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This ADRA1B antibody is un-conjugated

Application

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

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    1st Cytoplasmic Domain

    Specificity

    Reacts with human ADRA1B

    Cross-Reactivity (Details)

    BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC22A3 (50 % ).

    Purification

    Antigen affinity purified

    Immunogen

    Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human ADRA1B. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Marmoset (100%), Bovine (94%), Monkey (88%), Mouse (88%), Rat (88%), Hamster (88%)

    Isotype

    IgG
  • Application Notes

    Working dilution: IHC - P (6 μg/mL

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, Sodium azide 0.1 %

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-80 °C

    Storage Comment

    Long term: -70°C, Short term: +4°C
  • Target

    ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

    Alternative Name

    ADRA1B

    Background

    This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes

    UniProt

    P35368

    Pathways

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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