alpha 1b Adrenergic Receptor antibody (Adrenergic, alpha-1B-, Receptor) (1st Cytoplasmic Domain)

Details for Product anti-ADRA1B Antibody No. ABIN1731572
Antigen
Epitope
1st Cytoplasmic Domain
26
17
14
10
8
8
8
7
2
2
2
1
1
1
1
Reactivity
Human
140
57
54
7
6
6
5
5
4
4
4
2
1
1
Host
Rabbit
130
8
2
Clonality
Polyclonal
Conjugate
This alpha 1b Adrenergic Receptor antibody is un-conjugated
8
6
6
5
5
5
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
85
61
36
29
13
5
4
3
2
Options
Immunogen Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human ADRA1B. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Marmoset (100%), Bovine (94%), Monkey (88%), Mouse (88%), Rat (88%), Hamster (88%)
Isotype IgG
Specificity Reacts with human ADRA1B
Cross-Reactivity (Details) BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC22A3 (50 % ).
Purification Antigen affinity purified
Antigen
Alternative Name ADRA1B (ADRA1B Antibody Abstract)
Background This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes
UniProt P35368
Pathways AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Application Notes

Working dilution: IHC - P (6 μg/mL

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, Sodium azide 0.1 %
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-80 °C
Storage Comment Long term: -70°C, Short term: +4°C
Supplier Images
Image no. 1 for anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (1st Cytoplasmic Domain) antibody (ABIN1731572) anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (1st Cytoplasmic Domain) antibody