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ADRA1B antibody (3rd Cytoplasmic Domain)

This anti-ADRA1B antibody is a Rabbit Polyclonal antibody detecting ADRA1B in ELISA and IHC (p). Suitable for Human.
Catalog No. ABIN1731573

Quick Overview for ADRA1B antibody (3rd Cytoplasmic Domain) (ABIN1731573)

Target

See all ADRA1B Antibodies
ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This ADRA1B antibody is un-conjugated

Application

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

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    3rd Cytoplasmic Domain

    Specificity

    Reacts with human ADRA1B

    Cross-Reactivity (Details)

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.

    Purification

    Antigen affinity purified

    Immunogen

    Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human ADRA1B. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (100%), Rat (100%), Bovine (100%)

    Isotype

    IgG
  • Application Notes

    Working dilution: ELISA, IHC - P (10 μg/mL)

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, Sodium azide 0.1 %

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-80 °C

    Storage Comment

    Long term: -70°C, Short term: +4°C
  • Target

    ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

    Alternative Name

    ADRA1B

    Background

    This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes

    UniProt

    P35368

    Pathways

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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