ADRA1B antibody (C-Term, Cytoplasmic Domain)

Catalog No. ABIN1731575

The Rabbit Polyclonal anti-ADRA1B antibody has been validated for ELISA and IHC (p). It is suitable to detect ADRA1B in samples from Human.

Quick Overview for ADRA1B antibody (C-Term, Cytoplasmic Domain) (ABIN1731575)

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADRA1B Antibody

Binding Specificity: C-Term, Cytoplasmic Domain

Specificity: Reacts with human ADRA1B

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Antigen affinity purified

Immunogen: Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human ADRA1B. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Monkey (95%), Marmoset (95%), Mouse (85%), Hamster (85%), Elephant (85%).

Isotype: IgG

Application Details

Application Notes:

Working dilution: ELISA, IHC - P (10 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Long term: -70°C, Short term: +4°C

Target Details for ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Alternative Name: ADRA1B

Background: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process