BMF antibody (AA 2-14)

Catalog No. ABIN1732353

The Rabbit Polyclonal anti-BMF antibody (ABIN1732353) specifically detects BMF in WB, IHC (p) and ICC. The antibody is reactive with Human samples.

Quick Overview for BMF antibody (AA 2-14) (ABIN1732353)

Target: BMF (Bcl2 Modifying Factor (BMF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-BMF Antibody

Binding Specificity: AA 2-14

Specificity: Reacts with the N-terminus part of human Bmf.

Purification: Purified

Immunogen: Peptide corresponding to aa 2-14 of human Bmf (accession no. NP_277038).

Isotype: IgG

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB (2 μg/mL) ICC (10 μg/mL)

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Alternative Name: Bmf

Background: In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiating the downstream apoptotic program. Bmf is constitutively expressed in many tissues.

Bcl-2-modifying factor Bcl 2-modifying factor Gene name: BMF

Gene ID: 90427

UniProt: Q96LC9