Synaptogyrin 1 antibody (AA 170-234)

Catalog No. ABIN1742188

This Mouse Monoclonal antibody specifically detects Synaptogyrin 1 in WB, ELISA and IP. It exhibits reactivity toward Human, Mouse, Rat and Hamster and has been mentioned in 2+ publications.

Quick Overview for Synaptogyrin 1 antibody (AA 170-234) (ABIN1742188)

Target: Synaptogyrin 1 (SYNGR1)

Reactivity: Human, Mouse, Rat, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This Synaptogyrin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Clone: 80-1

Product Details anti-Synaptogyrin 1 Antibody

Binding Specificity: AA 170-234

Purpose: Mouse anti-Synaptogyrin1 IgG

Specificity: Specific for synaptogyrin 1 with a weak side-reactivity towards tubulin.

Cross-Reactivity (Details): Reacts with: human (O43759), rat (Q62876), mouse (O55100), hamster. No signal: zebrafish. Other species not tested yet.

Purification: purified IgG

Immunogen: Recombinant protein corresponding to AA 170 to 234 from rat Synaptogyrin1 (UniProt Id: Q62876)

Isotype: IgG1

Application Details

Application Notes: WB:1 : 1000 ICC:not recommended IHC:not recommended IHC-P:not recommended ELISA:yes

Comment:

IP: In immunoprecipitation (but not in other assays) tubulin coprecipitates with synaptogyrin 1 in about equal proportions. This is due to a direct binding of the antibody to tubulin. ELISA: Suitable as capture antibody for sandwich-ELISA with ABIN1742189 as detector antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

References for anti-Synaptogyrin 1 antibody (ABIN1742188)

von Kriegstein, Schmitz: "The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina." in: Cell and tissue research, Vol. 311, Issue 2, pp. 159-73, (2003) (PubMed).

Stenius, Janz, Südhof, Jahn: "Structure of synaptogyrin (p29) defines novel synaptic vesicle protein." in: The Journal of cell biology, Vol. 131, Issue 6 Pt 2, pp. 1801-9, (1996) (PubMed).

Target Details for Synaptogyrin 1

Target: Synaptogyrin 1 (SYNGR1)

Alternative Name: Synaptogyrin1

Background:

Synonyms: p29, syngr1

Antigen Information: Synaptogyrin is a major synaptic vesicle membrane protein, tyrosine-phosphorylated

UniProt: Q62876

Pathways: Regulation of long-term Neuronal Synaptic Plasticity