Syntaxin 12/13 (AA 1-250) antibody

Catalog No. ABIN1742229

Cited in 6+ publications. The Rabbit Polyclonal anti-Syntaxin 12/13 antibody (ABIN1742229) specifically detects Syntaxin 12/13 in ICC, WB, IHC (p), IHC and IP. The antibody is reactive with Rat, Chicken, Hamster, Human and Mouse samples.

Quick Overview for Syntaxin 12/13 (AA 1-250) antibody (ABIN1742229)

Target: Syntaxin 12/13

Reactivity: Rat, Chicken, Hamster, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunocytochemistry (ICC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Grade: KD Validated

Product Details

Binding Specificity: AA 1-250

Purpose: Rabbit anti-Syntaxin12/13 antiserum

Specificity: Specific for syntaxin 12/13.

Cross-Reactivity (Details): Reacts with: human (Q86Y82), rat (G3V7P1), mouse (Q9ER00), hamster, chicken. Other species not tested yet.

Purification: antiserum

Immunogen: Recombinant protein corresponding to AA 1 to 250 from rat Syntaxin12/13 (UniProt Id: G3V7P1)

Application Details

Application Notes: WB:1 : 100 up to 1 : 1000 , IP:yes ICC:1 : 100 up to 1 : 500, IHC:1 : 500, IHC-P:1 : 500,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Brandhorst, Zwilling, Rizzoli, Lippert, Lang, Jahn: "Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 8, pp. 2701-6, (2006) (PubMed).

Bonanomi, Menegon, Miccio, Ferrari, Corradi, Kao, Benfenati, Valtorta: "Phosphorylation of synapsin I by cAMP-dependent protein kinase controls synaptic vesicle dynamics in developing neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 32, pp. 7299-308, (2005) (PubMed).

Vetrivel, Cheng, Lin, Sakurai, Li, Nukina, Wong, Xu, Thinakaran: "Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes." in: The Journal of biological chemistry, Vol. 279, Issue 43, pp. 44945-54, (2004) (PubMed).

Bared, Buechler, Boettcher, Dayoub, Sigruener, Grandl, Rudolph, Dada, Schmitz: "Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells." in: Molecular biology of the cell, Vol. 15, Issue 12, pp. 5399-407, (2004) (PubMed).

Riedel, Antonin, Fernandez-Chacon, Alvarez de Toledo, Jo, Geppert, Valentijn, Valentijn, Jamieson, Südhof, Jahn: "Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules." in: Molecular and cellular biology, Vol. 22, Issue 18, pp. 6487-97, (2002) (PubMed).

Target Details

Target: Syntaxin 12/13

Alternative Name: Syntaxin12/13

Background:

Synonyms: syntaxin 12, syntaxin12, syntaxin13, syntaxin 13, stx12, stx 12, stx13, stx 13, SNARES

Antigen Information: K.D. Syntaxin12/13 is a syntaxin family member functioning in the recycling of plasma membrane receptors

UniProt: G3V7P1