APP antibody (AA 756-770)

Catalog No. ABIN1742281

This Rabbit Polyclonal antibody specifically detects APP in WB, IHC, ICC and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Chicken and Frogand has been mentioned in 1 publication.

Quick Overview for APP antibody (AA 756-770) (ABIN1742281)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human, Mouse, Rat, Chicken, Frog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-APP Antibody

Binding Specificity: AA 756-770

Purpose: Rabbit anti-APP antibody

Specificity: Specific for APP.

Cross-Reactivity (Details): Reacts with: rat (P08592), mouse (P12023), chicken, frog, human (P05067). Other species not tested yet.

Purification: affinity purified

Immunogen: Synthetic peptide corresponding to AA 756 to 770 from rat APP (UniProt Id: P08592)

Application Details

Application Notes: WB:1 : 500 up to 1 : 1000

Comment:

IHC/IHC-P: The affinity purified antibody is highly recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-APP antibody (ABIN1742281)

Groemer, Thiel, Holt, Riedel, Hua, Hüve, Wilhelm, Klingauf: "Amyloid precursor protein is trafficked and secreted via synaptic vesicles." in: PLoS ONE, Vol. 6, Issue 4, pp. e18754, (2011) (PubMed).

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: APP

Background:

Synonyms: amyloid precursor protein

Antigen Information: K.O. APP is a protein involved in Alzheimer's disease

UniProt: P08592

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour