Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 207-366) antibody

Catalog No. ABIN1742306

The Rabbit Polyclonal anti- antibody has been validated for WB and ICC. It is suitable to detect in samples from Rat and Mouse. There is 1 publication available.

Quick Overview for Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 207-366) antibody (ABIN1742306)

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Grade: KD Validated

Product Details

Binding Specificity: AA 207-366

Purpose: Rabbit anti-RIM1 antibody

Specificity: Specific for RIM 1

Cross-Reactivity (Details): Reacts with: rat (Q9JIR4), mouse (Q99NE5). Other species not tested yet.

Purification: affinity purified

Immunogen: Recombinant protein corresponding to AA 207 to 366 from rat Rim1 (UniProt Id: Q9JIR4)

Application Details

Application Notes: WB:1 : 100 up to 1 : 500 IHC-P:not tested yet

Comment:

WB: Antibody 3 is recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References

Limbach, Laue, Wang, Hu, Thiede, Hultqvist, Kilimann: "Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 31, pp. E392-401, (2011) (PubMed).

Target Details

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Alternative Name: RIM1

Background:

Synonyms: Regulating synaptic membrane exocytosis protein 1, RIMS1, Rab-3-interacting molecule 1

Antigen Information: K.D. RIMs are Rab3 effector proteins of the cytomatrix at the active zone

UniProt: Q9JIR4

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity