Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 975-1025) antibody

Catalog No. ABIN7453183

This Rabbit Polyclonal antibody specifically detects Regulating Synaptic Membrane Exocytosis 1 in WB. It exhibits reactivity toward Mouse and Human.

Quick Overview for Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 975-1025) antibody (7453183)

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: AA 975-1025

Purpose: Rabbit anti-RIMS1/RIM1 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: Between AA 975 and 1025

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Alternative Name: RIMS1/RIM1

Background: Background: RIMS1 is a Rab effector involved in exocytosis (By similarity). It may act as scaffold protein that regulates neurotransmitter release at the active zone. RIMS1 is ssential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (By similarity) [taken from the Universal Protein Resource (UniProt) Q86UR5].

Gene ID: 22999

UniProt: Q86UR5

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity