Abeta-pE3 (AA 3-7) antibody

Catalog No. ABIN1742434

This Mouse Monoclonal antibody specifically detects Abeta-pE3 in IHC (p), WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Abeta-pE3 (AA 3-7) antibody (ABIN1742434)

Target: Abeta-pE3

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 70D7

Product Details

Binding Specificity: AA 3-7

Purpose: Mouse anti-Abeta-pE3 IgG

Specificity: Recognizes specific oligomeric structures formed preferentially by Abeta-pE3.

Cross-Reactivity (Details): Reacts with: human (P05067), rat (P08592), mouse (P12023). Other species not tested yet.

Purification: purified IgG

Immunogen: Synthetic peptide corresponding to AA 3 to 7 from human Abeta-pE3 (UniProt Id: P05067)

Isotype: IgG3

Application Details

Application Notes: WB:1 : 1000 , IP:not tested yet ICC:not tested yet IHC:1 : 100, IHC-P:1 : 500,

Comment:

WB: Detects purified Abeta pE3. Complex samples like brain extracts still have to be tested.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Azide was added before lyophilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

Target Details

Target: Abeta-pE3

Background:

Synonyms: pE3-Abeta, pyro-Glu-Abeta, pGlu-Abeta, Abeta(3(pE)-40/42), pyro-Abeta

Antigen Information: Abeta peptides are major components of neuritic plaques in Alzheimer's disease

UniProt: P05067