GABRA2 antibody (AA 29-37)

Catalog No. ABIN1742454

Cited in 2+ publications. The Guinea Pig Polyclonal anti-GABRA2 antibody (ABIN1742454) specifically detects GABRA2 in WB, ICC, IP and IHC (fro). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GABRA2 antibody (AA 29-37) (ABIN1742454)

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Reactivity: Human, Rat, Mouse

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This GABRA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GABRA2 Antibody

Binding Specificity: AA 29-37

Purpose: anti-GABA-A receptor alpha2

Specificity: Specific for GABA-A receptor alpha2.

Cross-Reactivity (Details): Reacts with: human (P47869), rat (P23576), mouse (P26048). Other species not tested yet.

Purification: antiserum

Immunogen: Synthetic peptide corresponding to AA 29 to 37 from rat GABA-A receptor alpha2 (UniProt Id: P23576)

Application Details

Application Notes: WB:1 : 1000 ,

Comment:

WB: This protein aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples. ICC: This antibody is suitable for the surface staining of living cells. After washing cells with bound antibodies, they can be fixed and visualized with secondary reagents.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-GABRA2 antibody (ABIN1742454)

Wefelmeyer, Cattaert, Burrone: "Activity-dependent mismatch between axo-axonic synapses and the axon initial segment controls neuronal output." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 31, pp. 9757-62, (2015) (PubMed).

Herrera-Molina, Sarto-Jackson, Montenegro-Venegas, Heine, Smalla, Seidenbecher, Beesley, Gundelfinger, Montag: "Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65." in: The Journal of biological chemistry, Vol. 289, Issue 13, pp. 8973-88, (2014) (PubMed).

Target Details for GABRA2

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Alternative Name: GABA-A receptor alpha2

Background: Gabra2, GABA receptor

UniProt: P23576