This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GABRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the C-terminal region of human GABRA2.
C630048P16Rik antibody, Gabra-2 antibody, gamma-aminobutyric acid type A receptor alpha2 subunit antibody, gamma-aminobutyric acid type A receptor alpha1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 2 S homeolog antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 antibody, GABRA2 antibody, GABRA1 antibody, gabra2 antibody, Gabra2 antibody, gabra2.S antibody
Background
GABRA2 is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.