GABRA2 antibody (Middle Region)

Catalog No. ABIN2792259

Cited in 2+ publications. The Rabbit Polyclonal anti-GABRA2 antibody (ABIN2792259) specifically detects GABRA2 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Cow, Horse and Rabbit samples.

Quick Overview for GABRA2 antibody (Middle Region) (ABIN2792259)

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRA2 Antibody

Binding Specificity: Middle Region

Sequence: PMDAHSCPLK FGSYAYTTSE VTYIWTYNAS DSVQVAPDGS RLNQYDLLGQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GABRA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GABRA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 451 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GABRA2 antibody (ABIN2792259)

Kitayama, Morita, Sultana, Kikushige, Mgita, Ueno, Hirata, Kanematsu: "Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice." in: Molecular pain, Vol. 9, pp. 23, (2013) (PubMed).

Tian, Chen, Cross, Edenberg: "Alternative splicing and promoter use in the human GABRA2 gene." in: Brain research. Molecular brain research, Vol. 137, Issue 1-2, pp. 174-83, (2005) (PubMed).

Target Details for GABRA2

Target: GABRA2 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 2 (GABRA2))

Alternative Name: GABRA2

Background: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the gaba/benzodiazepine receptor and opening an integral chloride channel.
Protein Interaction Partner: UBQLN1,
Protein Size: 451

Molecular Weight: 51 kDa

Gene ID: 2555

NCBI Accession: NM_000807, NP_000798

UniProt: P47869