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Cytokeratin 18 antibody (Keratin 18) (Internal Region) Primary Antibody

Verified KRT18 Reactivity: Human, Pig ELISA, IHC, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN1781972
$451.79
Plus shipping costs $45.00
100 μg
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  • Target See all Cytokeratin 18 (KRT18) Antibodies
    Cytokeratin 18 (KRT18)
    Binding Specificity
    • 25
    • 15
    • 14
    • 14
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 324
    • 157
    • 125
    • 63
    • 43
    • 42
    • 37
    • 33
    • 30
    • 26
    • 24
    • 22
    • 22
    • 22
    • 9
    • 9
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Pig
    Host
    • 186
    • 158
    • 6
    • 6
    • 2
    • 1
    Goat
    Clonality
    • 202
    • 157
    Polyclonal
    Conjugate
    • 165
    • 29
    • 23
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    This Cytokeratin 18 antibody is un-conjugated
    Application
    • 224
    • 135
    • 131
    • 108
    • 82
    • 69
    • 58
    • 54
    • 42
    • 40
    • 33
    • 28
    • 12
    • 10
    • 8
    • 7
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Purpose
    keratin 18
    Sequence
    EELDKYWSQQ IE
    Specificity
    Reported variants represent identical protein: NP_000215.1, NP_954657.1.
    Predicted Reactivity
    Human, Mouse, Rat, Dog, Pig, Cow
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Isotype
    IgG
  • Application Notes

    DS WB Results: Approx 48 kDa band observed in lysates of cell lines A431, HeLa, MCF7 (calculated MW of 48.1 kDa according to NP_000215.1) and approx 45 kDa in lysates of Pig Liver (calculated MW of 47.4 kDa according to XP_005652636.2). Recommended concentration: 0.1-0.3 μg/mL.

    DS IHC Results: Paraffin embedded Human Breast, Placenta and Small Intestine. Recommended concentration: 5 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:32000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Target
    Cytokeratin 18 (KRT18)
    Alternative Name
    KRT18 (KRT18 Products)
    Synonyms
    CK18, K18, Krt1-18, CYK18, DreK18, cb83, dapk1, sb:cb83, wu:fa13f02, wu:fb36b04, krt18, MGC64569, MGC75922, KRT18, keratin 18, keratin 18, type I L homeolog, keratin 18, type I, keratin, type I cytoskeletal 18, K18, simple type I keratin, Keratin, type I cytoskeletal 18, Krt18, KRT18, krt18, krt18.L, LOC700569, LOC100136778, k1c18, LOC100008885
    Background
    KRT18, keratin 18, CYK18, K18, CK-18, cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, cytokeratin 18, cytokeratin-18, keratin, type I cytoskeletal 18, keratin-18
    Molecular Weight
    Expected molecular weight: 48 kDa
    Gene ID
    3875
    NCBI Accession
    NP_000215
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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