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C4BPA antibody

C4BPA Reactivity: Human IHC (p), EIA Host: Mouse Monoclonal 10-07-14 unconjugated
Catalog No. ABIN181109
  • Target See all C4BPA Antibodies
    C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))
    Reactivity
    • 37
    • 4
    • 1
    Human
    Host
    • 37
    • 2
    Mouse
    Clonality
    • 38
    • 1
    Monoclonal
    Conjugate
    • 14
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C4BPA antibody is un-conjugated
    Application
    • 28
    • 22
    • 17
    • 13
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes complement component 4 binding protein (C4bp).
    Characteristics
    Synonyms: C4BPA, C4BP, Proline-rich protein, PRP
    Purification
    Affinity Chromatography on Protein A.
    Immunogen
    Native Human C4 binding protein. Genename: C4BP
    Clone
    10-07-14
    Isotype
    IgG2b
    Top Product
    Discover our top product C4BPA Primary Antibody
  • Application Notes
    ELISA. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Borate buffered saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))
    Alternative Name
    C4b-Binding Protein alpha (C4BPA Products)
    Synonyms
    CRES antibody, c4bp antibody, C4BP antibody, PRP antibody, complement component 4 binding protein, alpha chain antibody, C4b-binding protein alpha chain antibody, complement component 4 binding protein alpha antibody, complement component 4 binding protein, alpha antibody, LOC419851 antibody, c4bp antibody, C4BPA antibody, C4bpa antibody
    Background
    There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.Synonyms: C4BP, C4BPA, PRP, Proline-rich protein
    Gene ID
    722
    UniProt
    P04003
    Pathways
    Complement System
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